PE/Dazzle™ 594 anti-human B7-H4 Antibody
- 产品名称：
- PE/Dazzle™ 594 anti-human B7-H4 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 358112
- 产品应用：
- 358112
[价格]
| 规格 |
价格 |
库存 |
| 100tests |
￥ 4584 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle? 594 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* PE/Dazzle? 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) includes immunofluorescence2.
- Application References
(PubMed link indicates BioLegend citation) -
- Quandt D, et al. 2011. Clin. Cancer Res. 17:3100.
- Smith JB, et al. 2014. Gynecol. Oncol. 134:181. (FC, IF)
- RRID
- AB_2564337 (BioLegend Cat. No. 358112)
- Structure
- Type I transmembrane protein, member of the B7 family, one IgV-like, one IgC-like domain
- Distribution
-
Activated T cells, B cells, monocytes, and dendritic cells; different cancer types including melanoma, renal, gastric, breast and ovarian
- Function
- Inhibits T cell proliferation, cytokine secretion, and development of cytotoxicity
- Cell Type
- B cells, Dendritic cells, Monocytes, T cells, Tregs
- Biology Area
- Costimulatory Molecules, Immunology
- Antigen References
-
1. Fauci JM, et al. 2012. Gynecol. Oncol. 127:420.
2. Chen C, et al. 2012. J. Immunother. 35:354.
3. Guo G, et al. 2012. Clin. Rheumatol. 31:271.
4. Arigami T, et al. 2010. J. Surg. Oncol. 102:748.
- Gene ID
- 79679 View all products for this Gene ID
- UniProt
- View information about B7-H4 on UniProt.org
