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PE/Dazzle™ 594 anti-human B7-H4 Antibody
产品名称:
PE/Dazzle™ 594 anti-human B7-H4 Antibody
产品类别:
抗体
产品编号:
358112
产品应用:
358112
[价格]
规格 价格 库存
100tests ¥ 4584 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Dazzle? 594 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* PE/Dazzle? 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) includes immunofluorescence2.

Application References

(PubMed link indicates BioLegend citation)
  1. Quandt D, et al. 2011. Clin. Cancer Res. 17:3100.
  2. Smith JB, et al. 2014. Gynecol. Oncol. 134:181. (FC, IF)
RRID
AB_2564337 (BioLegend Cat. No. 358112)

Antigen Details

Structure
Type I transmembrane protein, member of the B7 family, one IgV-like, one IgC-like domain
Distribution

Activated T cells, B cells, monocytes, and dendritic cells; different cancer types including melanoma, renal, gastric, breast and ovarian

Function
Inhibits T cell proliferation, cytokine secretion, and development of cytotoxicity
Cell Type
B cells, Dendritic cells, Monocytes, T cells, Tregs
Biology Area
Costimulatory Molecules, Immunology
Antigen References

1. Fauci JM, et al. 2012. Gynecol. Oncol. 127:420.
2. Chen C, et al. 2012. J. Immunother. 35:354.
3. Guo G, et al. 2012. Clin. Rheumatol. 31:271.
4. Arigami T, et al. 2010. J. Surg. Oncol. 102:748.

Gene ID
79679 View all products for this Gene ID
UniProt
View information about B7-H4 on UniProt.org

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