首页 > 抗体蛋白 > 抗体
APC anti-mouse CD276 (B7-H3) Antibody
产品名称:
APC anti-mouse CD276 (B7-H3) Antibody
产品类别:
抗体
产品编号:
135607
产品应用:
135607
[价格]
规格 价格 库存
25µg ¥ 1788 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse B7-H3 transfected L cell and P815
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.75 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Hashiguchi M, et al. 2008. Proc Natl Acad Sci USA. 105(30):10495.
  2. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
Product Citations
  1. Sitnik S, et al. 2020. Mol Ther Oncolytics. 17:190. PubMed
  2. Wang C, et al. 2021. Cell Stem Cell. . PubMed
RRID
AB_2566062 (BioLegend Cat. No. 135607) AB_2566063 (BioLegend Cat. No. 135608)

Antigen Details

Structure
A 49.7 kD member of the B7 family of the Ig superfamily proteins.
Distribution

Mostly expressed on professional APCs, including B cells, macrophages, and dendritic cells at low level.

Function
Provides a stimulatory signal to T cells, plays a negative regulatory role in T cell responses as well.
Ligand/Receptor
The receptor has not been completely identified, but it seems to be expressed on activated T cells.
Cell Type
Antigen-presenting cells, B cells, Dendritic cells
Biology Area
Cell Biology, Immunology, Signal Transduction, Costimulatory Molecules
Molecular Family
CD Molecules
Antigen References

1. Nagashima O, et al. 2008. J. Immunol. 181:4062
2. Prasad DVR, et al. 2004. J. Immunol. 173:2500
3. Sun M, et al. 2002. J. Immunol. 168:6294
4. Xu J, et al. 2006. Cellular and Molecular Immunology. 3(3):235
5. Ford JW, et al. 2009. Curr Opin Immunol. 21(1):38
6. Leitner J, et al. 2009. Eur. J. Immunol. 2009. 39(7):1754

Gene ID
102657 View all products for this Gene ID
UniProt
View information about CD276 on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线