PE anti-human CD254 (TRANCE, RANKL) Antibody
- 产品名称：
- PE anti-human CD254 (TRANCE, RANKL) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 347503
- 产品应用：
- 347503
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2052 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- RANKL-transfected L cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats of this clone) include: ELISA and immunohistochemical staining of paraffin-embedded tissue sections2.
- Application References
(PubMed link indicates BioLegend citation) -
- Kanamaru F, et al. 2004. Immunol. Lett. 94:239.
- Mueller A, et al. 2014. Arthritis Res. Ther. 16:R55. (IHC) PubMed
- Product Citations
-
- Lee WS, et al. 2020. Arthritis Rheumatol. 72:1493. PubMed
- Meng Y,et al. 2017. Cell Death Dis. . 10.1038/cddis.2017.505. PubMed
- Liao HQ, et al. 2021. Am J Reprod Immunol. 86:e13406. PubMed
- Hernndez DC, et al. 2021. Immunity. :. PubMed
- Vanoni G, et al. 2021. eLife. 10:00. PubMed
- Kenty JH, et al. 2021. STAR Protocols. 2(3):100675. PubMed
- RRID
- AB_2256265 (BioLegend Cat. No. 347503) AB_2256264 (BioLegend Cat. No. 347504)
- Structure
- A TNF superfamily member.
- Distribution
-
Expressed on osteoblasts and activated T cells.
- Function
- Plays an important role in osteoblast differentiation and bone resorption, regulates the interactions between T cells and dendritic cells, and T cells and B cells.
- Ligand/Receptor
- RANK, OPG.
- Cell Type
- T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokines/Chemokines
- Antigen References
-
1. Wiethe C, et al. 2003. J. Immunol. 171:4121
2. Page G, et al. 2005. Arthritis Rheum. 52:2307
3. Ji JD, et al. 2009. J. Immunol. 183:7223
- Gene ID
- 8600 View all products for this Gene ID
- UniProt
- View information about CD254 on UniProt.org
