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Purified anti-human CD180 (RP105) Antibody
产品名称:
Purified anti-human CD180 (RP105) Antibody
产品类别:
抗体
产品编号:
312902
产品应用:
312902
[价格]
规格 价格 库存
100µg ¥ 2328 1

产品详情

Product Details

Verified Reactivity
Human, Cynomolgus, Rhesus
Reported Reactivity
Baboon, African Green
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human RP105 complexed with mouse MD-1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
ICFC, IHC-F, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: intracellular staining1, immunoprecipitation1, immunohistochemistry1 of acetone-fixed frozen tissue sections, B cell activation1, protection from apoptosis induced by radiation or dexamethasone, and induction of the costimulatory molecule CD80 (B7-1)1. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 312913 and 312914).

Application References

(PubMed link indicates BioLegend citation)
  1. Miura Y, et al. 1998. Blood 92:2815.
  2. Indrevaer RL, et al. 2013. J. Immunol. 191:3624. PubMed
Product Citations
  1. Kikuchi J, et al. 2018. Cancer Res. 78:1766. PubMed
  2. Indrev?r R, et al. 2013. J Immunol. 191:3624. PubMed
  3. Gilljam KM, et al. 2020. J Immunol. 2133:204. PubMed
  4. Holm K,et al. 2017. PLoS One. 10.1371/journal.pone.0185708. PubMed
  5. Indrev?r R, et al. 2015. J Immunol. 195: 2601-2611. PubMed
RRID
AB_2228772 (BioLegend Cat. No. 312902)

Antigen Details

Structure
Member of the toll-like receptor family, 105 kD
Distribution

B cells, monocytes/macrophages, and dendritic cells

Function
Signaling protein involved in innate immunity
Ligand/Receptor
LPS
Cell Type
B cells, Dendritic cells, Macrophages, Monocytes
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Miura Y, et al. 1998. Blood 92:2815.

Gene ID
4064 View all products for this Gene ID
UniProt
View information about CD180 on UniProt.org

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