Purified anti-human Jagged 2 Antibody
- 产品名称:
- Purified anti-human Jagged 2 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 346902
- 产品应用:
- 346902
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human Jagged2-transfected CHO cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2028550 (BioLegend Cat. No. 346902)
- Structure
- A single pass transmembrane protein consisting of a large extracellular N-terminal which includes the DSL domain, followed by a tandem array of EGF-like repeats (ELRs) and cysteine-rich domain (CRD).
- Distribution
-
Expressed on lymphoma cells and some other tumor cells.
- Function
- Regulate cell fate decision for various cell developments, including myogenesis, neurogenesis, and lymphocyte development.
- Ligand/Receptor
- Notch molecules
- Biology Area
- Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Innate Immunity
- Antigen References
-
1. Moriyama Y et al. 2008. Int J. Immunol. 20:763
2. Ehebauer MT. et al. 2006. Biochem J 392:13
3. Shimizu K et al. 2000. Mol Cell Biology 20:18
4. Hellstrom M et al. 2007. Nature 445:776
5. Luo B et al. 1997. Mol Cell Biol. 17:6057
6. Stanley P et al. 2009. Immunol. Rev. 230(1):201
- Gene ID
- 3714 View all products for this Gene ID
- UniProt
- View information about Jagged 2 on UniProt.org