APC anti-human Delta-like protein 4 (DLL4) Antibod
- 产品名称：
- APC anti-human Delta-like protein 4 (DLL4) Antibod
- 产品类别：
- 抗体
- 产品编号：
- 346507
- 产品应用：
- 346507
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1788 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human DLL4
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications for the relevant formats include: blocking of DLL4 binding to Notch 1 and Notch 4.
- Application References
(PubMed link indicates BioLegend citation) -
- Yamanda S, et al. 2009. Blood 113:3631.
- Product Citations
-
- Bagheri V et al. 2018. Journal of cellular physiology. 233(10):7036-7046 . PubMed
- Xiong H, et al. 2021. Theranostics. 11:1594. PubMed
- RRID
- AB_11204421 (BioLegend Cat. No. 346507) AB_11204071 (BioLegend Cat. No. 346508)
- Structure
- Type I transmembrane protein whose extracellular domain contains a DSL domain and eight tandem EGF repeats
- Distribution
- Vascular endothelium, neural epithelium, adrenal cortex, spleen, and lymph nodes; highly expressed in some types of bladder, breast and renal carcinomas
- Function
- Vascular development and homeostasis
- Ligand/Receptor
- Notch 1 and Notch 4
- Cell Type
- Epithelial cells, Endothelial cells, Dendritic cells, Tregs
- Biology Area
- Angiogenesis, Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules
- Antigen References
-
1. Beck RC, et al. 2009. Biol Blood Marrow Transplant. 15:1026.
2. Mazella J, et al. 2008. Endocrinology. 149:15.
3. Noguera-Troise I, et al. 2006. Nature 444:1032.
4. Sugimoto A, et al. 2006. Exp Hematol. 34:424.
5. Liu ZJ, et al. 2003. Mol Cell Biol. 23:14.
- Gene ID
- 54567 View all products for this Gene ID
- UniProt
- View information about DLL4 on UniProt.org
