Alexa Fluor® 488 anti-mouse PD-1H (VISTA) Anti
- 产品名称：
- Alexa Fluor® 488 anti-mouse PD-1H (VISTA) Anti
- 产品类别：
- 抗体
- 产品编号：
- 143719
- 产品应用：
- 143719
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- PD-1H- IgG Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: inhibition of graft vs host disease (GVHD), Western blotting, and immunohistochemical staining of paraffin embedded tissue sections.
- Application References
(PubMed link indicates BioLegend citation) -
- Flies DB, et al. 2011. J. Immunol. 187:1537.
- Product Citations
-
- Henkle TR, et al. 2021. Cancer Res. 81:4560. PubMed
- RRID
- AB_2728164 (BioLegend Cat. No. 143719) AB_2728165 (BioLegend Cat. No. 143720)
- Structure
- Type I transmembrane protein, member of the CD28 family
- Distribution
-
Macrophages, dendritic cells, neutrophils, NK cells, na?ve and activated T cells
- Function
- Negative regulator of the immune response
- Cell Type
- Macrophages, Dendritic cells, Neutrophils, NK cells, T cells
- Biology Area
- Immunology, Inhibitory Molecules
- Antigen References
-
1. Flies DB, et al. 2011. J. Immunol. 187:1537.
2. Wang Li, et al. 2011. J. Exp Med. 208:577.
- Gene ID
- 74048 View all products for this Gene ID
- UniProt
- View information about PD-1H on UniProt.org
