Purified anti-mouse FOXP3 Antibody
- 产品名称：
- Purified anti-mouse FOXP3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 126401
- 产品应用：
- 126401
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB?- Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by?Western blotting. Western blotting, suggested working dilution(s): 0.01 - 1.0 ?g/mL antibody in dilution buffer. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
NOTE: For flow cytometric staining with this clone, True-Nuclear? Transcription Factor Buffer Set (Cat. No. 424401) offers improved staining and is highly recommended.
- Application References
(PubMed link indicates BioLegend citation) -
- Ono M, et al. 2007. Nature 446:685.
- Hori S, et al. 2003. Science 299:1057.
- Fontenot JD, et al. 2003 Nature Immunol 4:330.
- Fallarino F, et al. 2009. J. Immunol. 183:6033. PubMed
- Barber A, et al. 2009 J. Immunol. 183:6939. PubMed
- Nakashima H, et al. 2010. J. Immunol. 184:4637. PubMed
- Product Citations
-
- Toubai T, et al. 2017. Blood Adv. 1.095138889. PubMed
- Wan Mohd Zawawi WFA, et al. 2021. Sci Rep. 11:10278. PubMed
- Zhao J, et al. 2021. JCI Insight. 6:. PubMed
- Arnold IC, et al. 2018. J Exp Med. 215:2055. PubMed
- Draganov D, et al. 2021. NPJ Breast Cancer. 7:22. PubMed
- Chen L, et al. 2020. Front Immunol. 11:584458. PubMed
- Bittner-Eddy PD, et al. 2020. Front Immunol. 11:677. PubMed
- Drashansky TT, et al. 2019. Sci Adv. 5:eaaw0480. PubMed
- Artham S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L750:318. PubMed
- von Roemeling CA, et al. 2020. Nat Commun. 11:1508. PubMed
- Zhang X, et al. 2020. Int J Endocrinol. 2020:6543593. PubMed
- Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
- Pittala S, et al. 2018. Neoplasia. 9:20222. PubMed
- RRID
- AB_1089120 (BioLegend Cat. No. 126401) AB_1089119 (BioLegend Cat. No. 126402)
- Structure
- 50-55 kd protein. Forkhead/winged-helix transcription factor family, contains zinc finger and forkhead domains.
- Distribution
-
Nuclear; expressed in Treg cells.
- Function
- Master regulatory gene in Treg cell development, crucial for immune homeostasis.
- Interaction
- Interacts with DNA
- Cell Type
- Tregs
- Biology Area
- Immunology
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Ono M, et al. 2007. Nature 446:685.
2. Hori S, et al. 2003. Science 299:1057.
3. Fontenot JD, et al. 2003 Nature Immunol 4:330.
- Regulation
- Present at high level in T reg cells. Induced by T cell activation.
- Gene ID
- 20371 View all products for this Gene ID
- UniProt
- View information about FOXP3 on UniProt.org
