FITC anti-mouse CD45RB Antibody
- 产品名称:
- FITC anti-mouse CD45RB Antibody
- 产品类别:
- 抗体
- 产品编号:
- 151607
- 产品应用:
- 151607
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- anti-Ig activated murine B cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Birkeland ML, et al. 1988. J. Mol. Cell. Immunol. 4:71.
- Birkeland ML, et al. 1989. Proc. Natl. Acad. Sci. USA 86:6734.
- Lazarovits AI, et al. 1999. Kidney Int. 55:1303.
- RRID
- AB_2616741 (BioLegend Cat. No. 151607) AB_2616742 (BioLegend Cat. No. 151608)
- Structure
- Tyrosine phosphatases, type I transmembrane, 220 kD (exon 5 splicing of CD45 gene).
- Distribution
-
Thymocytes, T cell subset, B cells, monocytes/macrophages, granulocytes, and dendritic cells.
- Function
- Enhances TCR and BCR signaling.
- Ligand/Receptor
- Galectin-1, CD2, CD3, and CD4.
- Cell Type
- Thymocytes, T cells, B cells, Monocytes, Macrophages, Dendritic cells
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Inhibitory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Lee KM, et al. 2014. Cell Transplant. 23:51.
2. Kamanaka M, et al. 2011. J. Exp. Med. 208:1027.
3. Gagliani N, et al. 2011. PLoS One 6(12):e28434.
4. Ten Hove T, et al. 2004. J. Leuko. Biol. 75:1010.
5. Ogilvy S, et al. 2003. J. Immunol. 171:1792.
- Gene ID
- 19264 View all products for this Gene ID
- UniProt
- View information about CD45RB on UniProt.org