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FITC anti-mouse CD45RB Antibody
产品名称:
FITC anti-mouse CD45RB Antibody
产品类别:
抗体
产品编号:
151607
产品应用:
151607
[价格]
规格 价格 库存
50µg ¥ 648 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
anti-Ig activated murine B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Birkeland ML, et al. 1988. J. Mol. Cell. Immunol. 4:71.
  2. Birkeland ML, et al. 1989. Proc. Natl. Acad. Sci. USA 86:6734.
  3. Lazarovits AI, et al. 1999. Kidney Int. 55:1303.
RRID
AB_2616741 (BioLegend Cat. No. 151607) AB_2616742 (BioLegend Cat. No. 151608)

Antigen Details

Structure
Tyrosine phosphatases, type I transmembrane, 220 kD (exon 5 splicing of CD45 gene).
Distribution

Thymocytes, T cell subset, B cells, monocytes/macrophages, granulocytes, and dendritic cells.

Function
Enhances TCR and BCR signaling.
Ligand/Receptor
Galectin-1, CD2, CD3, and CD4.
Cell Type
Thymocytes, T cells, B cells, Monocytes, Macrophages, Dendritic cells
Biology Area
Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Inhibitory Molecules
Molecular Family
CD Molecules
Antigen References

1. Lee KM, et al. 2014. Cell Transplant. 23:51.
2. Kamanaka M, et al. 2011. J. Exp. Med. 208:1027.
3. Gagliani N, et al. 2011. PLoS One 6(12):e28434.
4. Ten Hove T, et al. 2004. J. Leuko. Biol. 75:1010.
5. Ogilvy S, et al. 2003. J. Immunol. 171:1792.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45RB on UniProt.org

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