FITC anti-mouse CD19 Antibody
- 产品名称：
- FITC anti-mouse CD19 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 101505
- 产品应用：
- 101505
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- mouse CD19+ pre-B cell line 300.19
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation3, and in vitro costimulation (synergistic with anti-IgM) of B cell activation1,2.
- Application References
(PubMed link indicates BioLegend citation) -
- Sato S, et al. 1997. J. Immunol. 158:4662. (Costim)
- Sato S, et al. 1997. P. Natl. Acad. Sci. USA 94:13158. (Costim)
- Krop I, et al. 1996. Eur. J. Immunol. 26:238. (IP)
- Sato S, et al. 1996. J. Immunol. 157:4371.
- Stolk M, et al. 2006. J. Leukoc. Biol. doi:10.1189/jlb.1205739. (FC)
- Shime H, et al. 2012. PNAS. 109:2066. PubMed.
- Product Citations
-
- Platt DJ, et al. 2021. Cell Reports. 35(6):109113. PubMed
- Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
- Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
- Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
- Fu Z, et al. 2021. Cell Res. 31:631. PubMed
- Shahzad KA, et al. 2018. Drug Deliv. 25:703. PubMed
- Zeis P, et al. 2020. Immunity. 53:775. PubMed
- Herder V, et al. 2012. J Neuroimmunol. 249:27. PubMed
- Rivera CA, et al. 2022. Immunity. 55:129. PubMed
- Jing Y, et al. 2019. J Allergy Clin Immunol. 144:1377. PubMed
- Du Z, et al. 2020. J Allergy Clin Immunol. . PubMed
- RRID
- AB_312824 (BioLegend Cat. No. 101505) AB_312825 (BioLegend Cat. No. 101506)
- Structure
- Ig superfamily, associates with CD21 and CD81, 95 kD
- Distribution
-
Pro-B cells to mature B cells (during development), follicular dendritic cells
- Function
- Modulates B cell activation and differentiation
- Ligand/Receptor
- CD21, CD81, Leu-13
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Immunology, Costimulatory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341.
2. Krop I, et al. 1996. Eur. J. Immunol. 26:238.
3. Krop I, et al. 1996. J. Immunol. 157:48.
4. Tedder TF,et al. 1994. Immunol. Today 15:437.
- Gene ID
- 12478 View all products for this Gene ID
- UniProt
- View information about CD19 on UniProt.org
