Purified anti-mouse FcεRIα Antibody
- 产品名称：
- Purified anti-mouse FcεRIα Antibody
- 产品类别：
- 抗体
- 产品编号：
- 134301
- 产品应用：
- 134301
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for relevant formats of this clone) include: depletion2, immunohistochemistry of frozen sections (OCT embedded2).
- Application References
(PubMed link indicates BioLegend citation) -
- Obata K, et al. 2007. Blood 110:913 (FC)
- Sokol CL, et al. 2008. Nat. Immunol. 9:310 (FC, Deplete, IHC)
- Chen J, et al. 2009. J. Biol. Chem.. 284:5763 (FC)
- Product Citations
-
- Guo R, et al. 2020. Cell Res. 30:21. PubMed
- Crawford G, et al. 2018. Nat Immunol. 1.388194444. PubMed
- Peng V, et al. 2020. J Biol Chem. 295:14866. PubMed
- Xiong H, et al. 2021. Theranostics. 11:1594. PubMed
- Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
- Matsuba S, et al. 2017. Front Immunol. . 10.3389/fimmu.2017.01538. PubMed
- Satoh–Takayama N, et al. 2020. Immunity. 52(4):635-649. PubMed
- RRID
- AB_1626076 (BioLegend Cat. No. 134301) AB_1626078 (BioLegend Cat. No. 134302)
- Structure
- A transmembrane protein of Ig super family member
- Distribution
-
Expressed on mast and basophils.
- Function
- Play an important role in triggering IgE-mediated allergic reactions.
- Ligand/Receptor
- IgE
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
-
1. Arinobu Y, et al. 2005. P. Natl. Acad. Sci. USA 102:18105.
2. Yamaguchi M, et al. 2001. Int. Immunol. 13:843.
- Gene ID
- 2205 View all products for this Gene ID
- UniProt
- View information about FcepsilonRIalpha on UniProt.org
