PE/Cyanine7 anti-mouse FcεRIα Antibo
- 产品名称：
- PE/Cyanine7 anti-mouse FcεRIα Antibo
- 产品类别：
- 抗体
- 产品编号：
- 134317
- 产品应用：
- 134317
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for relevant formats of this clone) include: depletion2, immunohistochemistry of frozen sections (OCT embedded2).
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Obata K, et al. 2007. Blood 110:913 (FC)
- Sokol CL, et al. 2008. Nat. Immunol. 9:310 (FC, Deplete, IHC)
- Chen J, et al. 2009. J. Biol. Chem.. 284:5763 (FC)
- Product Citations
-
- Huang W, et al. 2015. J Allergy Clin Immunol. . PubMed
- Oh–Hora M, et al. 2019. J Immunol. 202:2616. PubMed
- Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
- Wu X, et al. 2018. J Biol Chem. 293:10425. PubMed
- Wiesner D, et al. 2015. PLoS Pathog. 11:1004701. PubMed
- Li Y, et al. 2021. Nat Commun. 0.843055556. PubMed
- Ebert S, et al. 2014. PLoS Pathog. 10:1004100. PubMed
- Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
- Zhu M, et al. 2015. J Immunol. 195: 4492 - 4502. PubMed
- Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
- Gubin MM, et al. 2018. Cell. 175:1014. PubMed
- Gentek R, et al. 2018. Immunity. 48:1160. PubMed
- Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
- López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
- Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
- RRID
- AB_10643996 (BioLegend Cat. No. 134317) AB_10640122 (BioLegend Cat. No. 134318)
- Structure
- A transmembrane protein of Ig super family member
- Distribution
-
Expressed on mast and basophils.
- Function
- Play an important role in triggering IgE-mediated allergic reactions.
- Ligand/Receptor
- IgE
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
-
1. Arinobu Y, et al. 2005. P. Natl. Acad. Sci. USA 102:18105.
2. Yamaguchi M, et al. 2001. Int. Immunol. 13:843.
- Gene ID
- 2205 View all products for this Gene ID
- UniProt
- View information about FcepsilonRIalpha on UniProt.org
