PE anti-mouse FcεRIα Antibody
- 产品名称：
- PE anti-mouse FcεRIα Antibody
- 产品类别：
- 抗体
- 产品编号：
- 134307
- 产品应用：
- 134307
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for relevant formats of this clone) include: depletion2, immunohistochemistry of frozen sections (OCT embedded2).
- Application References
(PubMed link indicates BioLegend citation) -
- Obata K, et al. 2007. Blood 110:913 (FC)
- Sokol CL, et al. 2008. Nat. Immunol. 9:310 (FC, Deplete, IHC)
- Chen J, et al. 2009. J. Biol. Chem.. 284:5763 (FC)
- Product Citations
-
- Sch?dlich IS, et al. 2022. iScience. 25:104470. PubMed
- Bratti M, et al. 2022. Front Immunol. 13:1029759. PubMed
- Starkl P, et al. 2020. Immunity. 53(4):793-804.e9. PubMed
- Shade K, et al. 2015. J Exp Med. 212:457. PubMed
- Mooney J, et al. 2015. Sci Rep. 5: 14603. PubMed
- Mantri CK, et al. 2019. J Clin Invest. 129:1094. PubMed
- Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
- Sch?fer B, et al. 2013. J Allergy Clin Immunol. 131:541. PubMed
- Jones T, et al. 2010. J Immunol. 185:1804. PubMed
- Convente MR, et al. 2018. J Bone Miner Res. 33:269. PubMed
- Becker W, et al. 2021. J Crohns Colitis. 15:1032. PubMed
- Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
- Cohen M et al. 2018. Cell. 175(4):1031-1044 . PubMed
- Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
- Walens A, et al. 2019. Elife. 8:e43653. PubMed
- Hardy SA, et al. 2019. PLoS One. 14:e0212230. PubMed
- Baier A, et al. 2014. J Leukoc Biol. 95:763. PubMed
- Strattan E, et al. 2020. Frontiers in Immunology. 2.131944444. PubMed
- RRID
- AB_1626104 (BioLegend Cat. No. 134307) AB_1626095 (BioLegend Cat. No. 134308)
- Structure
- A transmembrane protein of Ig super family member
- Distribution
-
Expressed on mast and basophils.
- Function
- Play an important role in triggering IgE-mediated allergic reactions.
- Ligand/Receptor
- IgE
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
-
1. Arinobu Y, et al. 2005. P. Natl. Acad. Sci. USA 102:18105.
2. Yamaguchi M, et al. 2001. Int. Immunol. 13:843.
- Gene ID
- 2205 View all products for this Gene ID
- UniProt
- View information about FcepsilonRIalpha on UniProt.org
