FITC anti-mouse FcεRIα Antibody
- 产品名称：
- FITC anti-mouse FcεRIα Antibody
- 产品类别：
- 抗体
- 产品编号：
- 134305
- 产品应用：
- 134305
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for relevant formats of this clone) include: depletion2, immunohistochemistry of frozen sections (OCT embedded2).
- Application References
(PubMed link indicates BioLegend citation) -
- Obata K, et al. 2007. Blood 110:913 (FC)
- Sokol CL, et al. 2008. Nat. Immunol. 9:310 (FC, Deplete, IHC)
- Chen J, et al. 2009. J. Biol. Chem.. 284:5763 (FC)
- Product Citations
-
- Kaur K, et al. 2021. Cell Rep. 37:110178. PubMed
- An SB, et al. 2022. Nat Commun. 13:5669. PubMed
- Morshed M, et al. 2014. J Immunol. 192:5314. PubMed
- Green DP, et al. 2019. Neuron. 101:412. PubMed
- Kornst?dt L, et al. 2021. Front Immunol. 11:607048. PubMed
- Kim HW, et al. 2022. Theranostics. 12:3316. PubMed
- Oka Y, et al. 2020. Sci Adv. 6:. PubMed
- Tsuchiya K, et al. 2019. Nat Commun. 10:2091. PubMed
- McCallion A, et al. 2022. Front Immunol. 13:961599. PubMed
- Koide S, et al. 2022. iScience. 25:103603. PubMed
- Sulsenti R, et al. 2021. Frontiers in Immunology. 12:622001. PubMed
- Damgaard RB et al. 2016. Cell. 166(5):1215-1230 . PubMed
- Shi J, et al. 2015. PLoS One. 10: 0131461. PubMed
- Brian BF 4th et al. 2019. Elife. 8 pii: e46043. PubMed
- Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
- Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
- Jaeger N, et al. 2020. Cell Rep. 33:108331. PubMed
- Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
- Zeng F, et al. 2021. J Invest Dermatol. 596:141. PubMed
- RRID
- AB_1626102 (BioLegend Cat. No. 134305) AB_1626108 (BioLegend Cat. No. 134306)
- Structure
- A transmembrane protein of Ig super family member
- Distribution
-
Expressed on mast and basophils.
- Function
- Play an important role in triggering IgE-mediated allergic reactions.
- Ligand/Receptor
- IgE
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
-
1. Arinobu Y, et al. 2005. P. Natl. Acad. Sci. USA 102:18105.
2. Yamaguchi M, et al. 2001. Int. Immunol. 13:843.
- Gene ID
- 2205 View all products for this Gene ID
- UniProt
- View information about FcepsilonRIalpha on UniProt.org
