APC anti-mouse FcεRIα Antibody
- 产品名称：
- APC anti-mouse FcεRIα Antibody
- 产品类别：
- 抗体
- 产品编号：
- 134315
- 产品应用：
- 134315
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for relevant formats of this clone) include: depletion2, immunohistochemistry of frozen sections (OCT embedded2).
- Application References
(PubMed link indicates BioLegend citation) -
- Obata K, et al. 2007. Blood 110:913 (FC)
- Sokol CL, et al. 2008. Nat. Immunol. 9:310 (FC, Deplete, IHC)
- Chen J, et al. 2009. J. Biol. Chem.. 284:5763 (FC)
- Product Citations
-
- Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
- Zhang S, et al. 2021. Cell. 184(8):2151-2166.e16. PubMed
- Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
- Ku MW, et al. 2020. Cell Host Microbe. 29(2):236-249.e6. PubMed
- Hams E, et al. 2014. Proc Natl Acad Sci U S A. 111:367. PubMed
- Medler TR et al. 2018. Cancer cell. 34(4):561-578 . PubMed
- Janela B, et al. 2019. Immunity. 50:1069. PubMed
- Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
- Hidaka T, et al. 2016. Nat Immunol. 18:64-73. PubMed
- Klein O, et al. 2019. J Allergy Clin Immunol. 144:1074. PubMed
- Shu Z, et al. 2020. Mar Drugs. 18:00. PubMed
- RRID
- AB_10640726 (BioLegend Cat. No. 134315) AB_10640121 (BioLegend Cat. No. 134316)
- Structure
- A transmembrane protein of Ig super family member
- Distribution
-
Expressed on mast and basophils.
- Function
- Play an important role in triggering IgE-mediated allergic reactions.
- Ligand/Receptor
- IgE
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
-
1. Arinobu Y, et al. 2005. P. Natl. Acad. Sci. USA 102:18105.
2. Yamaguchi M, et al. 2001. Int. Immunol. 13:843.
- Gene ID
- 2205 View all products for this Gene ID
- UniProt
- View information about FcepsilonRIalpha on UniProt.org
