Alexa Fluor® 647 anti-mouse FcεRI&alph
- 产品名称：
- Alexa Fluor® 647 anti-mouse FcεRI&alph
- 产品类别：
- 抗体
- 产品编号：
- 134309
- 产品应用：
- 134309
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
- Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for relevant formats of this clone) include: depletion2, immunohistochemistry of frozen sections (OCT embedded2).
- Application References
(PubMed link indicates BioLegend citation) -
- Obata K, et al. 2007. Blood 110:913 (FC)
- Sokol CL, et al. 2008. Nat. Immunol. 9:310 (FC, Deplete, IHC)
- Chen J, et al. 2009. J. Biol. Chem.. 284:5763 (FC)
- Product Citations
-
- Minutti CM, et al. 2019. Immunity. 50:645. PubMed
- Bratti M, et al. 2022. Front Immunol. 13:1029759. PubMed
- Dráberová L, et al. 2020. Front Immunol. 10:3068. PubMed
- Nurkhametova D, et al. 2019. Front Cell Neurosci. 13:45. PubMed
- Zhu YP et al. 2018. Cell reports. 24(9):2329-2341 . PubMed
- Kassas–Guediri A, et al. 2017. PLoS One. 12:e0173815. PubMed
- Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
- RRID
- AB_1626097 (BioLegend Cat. No. 134309) AB_1626093 (BioLegend Cat. No. 134310)
- Structure
- A transmembrane protein of Ig super family member
- Distribution
-
Expressed on mast and basophils.
- Function
- Play an important role in triggering IgE-mediated allergic reactions.
- Ligand/Receptor
- IgE
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
-
1. Arinobu Y, et al. 2005. P. Natl. Acad. Sci. USA 102:18105.
2. Yamaguchi M, et al. 2001. Int. Immunol. 13:843.
- Gene ID
- 2205 View all products for this Gene ID
- UniProt
- View information about FcepsilonRIalpha on UniProt.org
