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PE anti-human HLA-DM Antibody
产品名称:
PE anti-human HLA-DM Antibody
产品类别:
抗体
产品编号:
358003
产品应用:
358003
[价格]
规格 价格 库存
25tests ¥ 1608 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
MHC class II enriched organelles from the B cell line Pala.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Hammond C, et al. 1998. J. Immunol. 161:3282.
  2. Faubert A, et al. 2002. J. Biol. Chem. 277:2750.
  3. Xiu F, et al. 2011. J. Immunol. 187:1547.
Product Citations
  1. Rosskopf S, et al. 2016. Sci Rep. 6:31580. PubMed
  2. álvaro-Benito M, et al. 2020. Cell Mol Immunol. 17:133. PubMed
RRID
AB_2562027 (BioLegend Cat. No. 358003) AB_2562028 (BioLegend Cat. No. 358004)

Antigen Details

Structure
Heterodimer comprising one α and one β chain.
Distribution
Antigen presenting cells.
Function
Facilitates the exchange of CLIP for the antigenic peptide in the grove of the MHC class II molecule, maintaining the tertiary structure of this molecule during the process.
Interaction
MHC class II
Cell Type
Antigen-presenting cells, B cells, Dendritic cells
Biology Area
Immunology
Molecular Family
MHC Antigens
Gene ID
3108 View all products for this Gene ID 3109 View all products for this Gene ID
UniProt
View information about HLA-DM on UniProt.org

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