PE/Cyanine7 anti-human CD141 (Thrombomodulin) Anti
- 产品名称：
- PE/Cyanine7 anti-human CD141 (Thrombomodulin) Anti
- 产品类别：
- 抗体
- 产品编号：
- 344109
- 产品应用：
- 344109
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2112 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Product Citations
-
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
- Forbester JL, et al. 2020. J Virol. 94:. PubMed
- Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed
- Mishra A, et al. 2018. J Allergy Clin Immunol. 142:1066. PubMed
- Janela B, et al. 2019. Immunity. 50:1069. PubMed
- Lee YS, et al. 2021. J Immunother Cancer. 9:. PubMed
- Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
- Lee J, et al. 2015. J Exp Med. 212:385. PubMed
- Breton G, et al. 2015. J Exp Med. 212:401. PubMed
- Leylek R, et al. 2020. Cell Rep. 32:108180. PubMed
- RRID
- AB_2561622 (BioLegend Cat. No. 344109) AB_2561623 (BioLegend Cat. No. 344110)
- Structure
- Single chain, type I membrane glycoprotein, 75 kD
- Distribution
-
Macrophages, monocytes, subset of myeloid dendritic cells, vascular endothelial cells, keratinocytes
- Function
- After thrombin binding, CD141 activates protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated.
- Interaction
- Protein C, Thrombin-activatable fibrinolysis inhibitor (TAFI), Platelet factor 4 (PF4)
- Ligand/Receptor
- Thrombin
- Cell Type
- Dendritic cells, Endothelial cells, Macrophages, Monocytes
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Suzuki K, et al. 1987. EMBO J. 6:1891.
2. Esmon CT, et al. 1989. J. Biol. Chem. 264:4743.
3. Delvaeye M, et al. 2009. N. Engl. J. Med. 361:345.
4. Shi CS, et al. 2008. Blood 112:3661.
5. Chen LC, et al. 2009. J. Infect. 58:368.
- Gene ID
- 7056 View all products for this Gene ID
- UniProt
- View information about CD141 on UniProt.org
