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Purified anti-ALDH1A1 Antibody
产品名称:
Purified anti-ALDH1A1 Antibody
产品类别:
抗体
产品编号:
861901
产品应用:
861901
[价格]
规格 价格 库存
25µg ¥ 1272 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Clone M562 was generated from a recombinant protein corresponding to amino acids in the N-terminal region from human ALDH1A1.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
IHC-P, ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 ?g per mL.?For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 0.5?- 5.0??g/mL?for chromogenic staining and 2.0?- 5.0??g/mL?for fluorescent staining is suggested.?For immunocytochemistry, a concentration range of 2.0?- 10?μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2801235 (BioLegend Cat. No. 861901) AB_2801236 (BioLegend Cat. No. 861902)

Antigen Details

Structure
ALDH1A1 is a 501 amino acid protein with a molecular mass of ~55 kD.
Distribution

Tissue Distribution: Liver, kidney, red blood cells, skeletal muscle, lung, breast, lens, stomach, brain, pancreas, testis, prostate, and ovary.
Cellular Distribution: Extracellular, cytosol, cytoskeleton, mitochondria, and nucleus.

Function
ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. ALDH1A1 is also responsible for the oxidation retinaldehyde to retinoic acid.
Cell Type
Endothelial cells, Oligodendrocytes
Biology Area
Neuroscience
Molecular Family
Aldehyde Dehydrogenases
Antigen References
  1. Xu SL, et al. Am J Cancer Res. 2015 Mar 15;5(4):1471-83.
  2. Olmez I, et al. J Cell Mol Med. 2015 Jun;19(6):1262-72.
  3. Sch?fer A, et al. Neuro Oncol. 2012 Dec;14(12):1452-64.
  4. Adam SA, et al. Brain Pathol. 2012 Nov;22(6):788-97.
Gene ID
216 View all products for this Gene ID
UniProt
View information about ALDH1A1 on UniProt.org

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