Purified anti-human CD11a/CD18 (LFA-1) Antibody
- 产品名称：
- Purified anti-human CD11a/CD18 (LFA-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 363402
- 产品应用：
- 363402
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Fibronectin-purified human monocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone m24 can be used as a reporter of the activation state of integrin receptor in response to exposure with Mg2+ or Mn2+.
- Application References
(PubMed link indicates BioLegend citation) -
- Hogg N. et al. 1985. Cell Immunol. 92:247.
- McDowall A. et al. 2003. J. Clin. Invest. 111:51.
- Product Citations
-
- Weulersse M, et al. 2020. Immunity. 53(4):824-839.e10. PubMed
- Assil S et al. 2019. Cell host & microbe. 25(5):730-745 . PubMed
- RRID
- AB_2564213 (BioLegend Cat. No. 363402)
- Structure
- Integrin family, 95KD, Ig superfamily
- Distribution
-
All leukocytes
- Function
- Adhesion
- Ligand/Receptor
- ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, fibrinogen
- Cell Type
- Dendritic cells, Leukocytes, Neutrophils
- Biology Area
- Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Anderson D, et al. 1987. Annu. Rev. Med. 38:175.
2. Springer T. 1994. Cell 76:301.
- Gene ID
- 16408 View all products for this Gene ID 16414 View all products for this Gene ID
- UniProt
- View information about CD18 on UniProt.org
