Alexa Fluor® 488 anti-human CD11a/CD18 (LFA-1)
- 产品名称：
- Alexa Fluor® 488 anti-human CD11a/CD18 (LFA-1)
- 产品类别：
- 抗体
- 产品编号：
- 363403
- 产品应用：
- 363403
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1764 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Fibronectin-purified human monocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Clone m24 can be used as a reporter of the activation state of integrin receptor in response to exposure with Mg2+ or Mn2+.
- Application References
(PubMed link indicates BioLegend citation) -
- Hogg N. et al. 1985. Cell Immunol. 92:247.
- McDowall A. et al. 2003. J. Clin. Invest. 111:51.
- Product Citations
-
- Bezverbnaya K, et al. 2021. Cytotherapy. 23:820. PubMed
- Weulersse M, et al. 2020. Immunity. 53(4):824-839.e10. PubMed
- Mancuso RV, et al. 2020. British Journal of Pharmacology. 177(12):2696-2711.. PubMed
- Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
- Zhichao Fan et al. 2019. Cell reports. 26(1):119-130 . PubMed
- Fan Z, et al. 2020. STAR Protoc. 1:100012. PubMed
- Chen EW, et al. 2019. Front Immunol. 10:1718. PubMed
- Murugesan S, et al. 2016. J Cell Biol. 215: 383 - 399. PubMed
- Wilton KM, et al. 2019. J Cell Sci. 133:jcs230508. PubMed
- RRID
- AB_2565288 (BioLegend Cat. No. 363403) AB_2565289 (BioLegend Cat. No. 363404)
- Structure
- Integrin family, 95KD, Ig superfamily
- Distribution
-
All leukocytes
- Function
- Adhesion
- Ligand/Receptor
- ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, fibrinogen
- Cell Type
- Dendritic cells, Leukocytes, Neutrophils
- Biology Area
- Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Anderson D, et al. 1987. Annu. Rev. Med. 38:175.
2. Springer T. 1994. Cell 76:301.
- Gene ID
- 16408 View all products for this Gene ID 16414 View all products for this Gene ID
- UniProt
- View information about CD18 on UniProt.org
