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首页 > 抗体蛋白 > 抗体
PE anti-mouse CD24 Antibody
产品名称：
PE anti-mouse CD24 Antibody
产品类别：
抗体
产品编号：
101807
产品应用：
101807
[价格]
规格 价格 库存
50µg ￥ 1032 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 mouse splenic T cells and concanavalin A-activated splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: Western blotting1, in vitro induction of thymocyte maturation2, complement-mediated cytotoxicity3, and immunohistochemistry of acetone-fixed frozen sections4, formalin-fixed paraffin-embedded sections5 and zinc-fixed paraffin-embedded sections10. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 101845 and 101846).

Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (WB)
  2. Crowley M, et al. 1989. Cell. Immunol. 118:108. (FA)
  3. Veillette A, et al. 1989. J. Exp. Med. 170:1671. (FA)
  4. Pandelakis A Flavell RA 1999 JEM 189:855 (FC, IHC)
  5. Liu JQ, et al. 2007 J. Immunol. 178:6227. (FC, IF)
  6. Chappaz S, et al. 2007. Blood doi:10.1182/blood-2007-02-074245. (FC) PubMed
  7. Rucci F, et al. 2010. Proc Natl Acad Sci USA. 107:3024. (FC) PubMed
  8. Teague TK, et al. 2010. Int Immunol. 22:387. (FC) PubMed
  9. Gracz AD, et al. 2010. Am J. Physiol Gastrointest Liver Physiol. 298:590. (FC) PubMed
  10. Chen CY, et al. 2008. Endocrinology. 10:1210. (FC, IHC) PubMed
  11. Qui Q, et al. 2010. J. Immunol. 184:1681. (FC) PubMed
Product Citations
  1. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  2. Howley BV, et al. 2018. Oncogene. 37:1308. PubMed
  3. Schmidt V, et al. 2021. J Cell Biol. 220:. PubMed
  4. Pokrovskii M, et al. 2020. EMBO J. 39:e104159. PubMed
  5. Chen J et al. 2018. Cell reports. 25(12):3393-3404 . PubMed
  6. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  7. Hao J et al. 2018. Cell metabolism. 28(5):689-705 . PubMed
  8. Bazett M, Haston M 2016. Sci Rep. 6:19189. PubMed
  9. Lichtenberger B, Watt M 2016. Nat Commun. 7:10537. PubMed
  10. Yasuoka T, et al. 2016. PLoS One. 11: 0157395. PubMed
  11. Ostendorf BN, et al. 2020. Nat Med. 26:1048. PubMed
  12. Sakaguchi S, et al. 2015. J Leukoc Biol. 97:635. PubMed
  13. Paiva RA, et al. 2021. Cell Reports. 35(2):108967. PubMed
  14. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  15. Chen F et al. 2018. Cell reports. 25(10):2775-2783 . PubMed
  16. Tavazoie MF, et al. 2018. Cell. 172:825. PubMed
  17. Aschman T, et al. 2021. Int J Mol Sci. 22:. PubMed
  18. Kang X, et al. 2022. J Immunol Res. 2022:8118577. PubMed
  19. Kondo M, et al. 2016. J Immunol. 196: 563 - 572. PubMed
  20. Andersen L, et al. 2020. Cell Reports. 29(13):4447-4459.e6.. PubMed
  21. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  22. Gu VW, et al. 2021. Stem Cell Reports. 16:106. PubMed
  23. Morikawa M, et al. 2016. PLoS One. 11:e0163607. PubMed
  24. Shissler SC, et al. 2020. Sci Rep. 10:8218. PubMed
  25. Jing Y, et al. 2021. Front Immunol. 12:651860. PubMed
  26. Baglaenko Y, et al. 2016. PLoS One. 11: 0150515. PubMed
  27. Katzmarski N, et al. 2021. Nat Immunol. 22:1382. PubMed
  28. Pal B, et al. 2021. Breast Cancer Res. 23:69. PubMed
  29. Leruste A, et al. 2020. Cancer Cell. 36(6):597-612.e8.. PubMed
  30. Trivedi S, et al. 2020. Elife. 9:00. PubMed
  31. Chen C, et al. 2008. Endocrinology. 150:492. PubMed
RRID
AB_312840 (BioLegend Cat. No. 101807) AB_312841 (BioLegend Cat. No. 101808)

Antigen Details

Structure
GPI-linked sialoglycoprotein, 35-45 kD
Distribution

B cells, granulyocytes, epithelial cells, thymocytes, monocytes, erythrocytes, dendritic cells

Function
Regulates B cell proliferation and differentiation
Ligand/Receptor
P-selectin, CD24
Cell Type
B cells, Dendritic cells, Epithelial cells, Erythrocytes, Granulocytes, Monocytes, Thymocytes
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Aigner S, et al. 1997. Blood 89:3385.
3. Hough MR, et al. 1996. J. Immunol. 156:479.
4. Liu Y, et al. 1992. J. Exp. Med. 175:437.

Gene ID
12484 View all products for this Gene ID
UniProt
View information about CD24 on UniProt.org

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