Purified anti-CD55 Antibody
- 产品名称：
- Purified anti-CD55 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 868801
- 产品应用：
- 868801
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 10 ?g per ml.?For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 2.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
When running WB, lysates should be loaded without DTT, and unboiled.
- RRID
- AB_2814625 (BioLegend Cat. No. 868801) AB_2814626 (BioLegend Cat. No. 868802)
- Structure
- CD55 is a 381 amino acid protein with predicted molecular mass of ~41 kD and observed molecular mass of ~55 kD.
- Distribution
-
Tissue Distribution: Predominantly expressed in the brain, lung, ovary, and placenta
Cellular Distribution: Plasma membrane, extracellular, and Golgi apparatus
- Function
- CD55 recognizes C4b and C3b fragments that are created during C3 and C4 activation, and indirectly blocks the formation of the membrane attack complex.
- Interaction
- Forms non-disulfide-linked, covalent homodimer.
- Ligand/Receptor
- CD97
- Cell Type
- Endothelial cells
- Biology Area
- Complement, Innate Immunity, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Blood Group Markers, CD Molecules, Golgi Markers, Innate Immune Signaling
- Antigen References
-
- Dho SH, et al. 2018. Immune Netw. 18(1):e11
- Nowicki B, et al. 2013. Adv Exp Med Biol. 735:83
- Piccoli AK, et al. 2011. Rev Bras Reumatol. 51(5):503
- Gene ID
- 1604 View all products for this Gene ID
- UniProt
- View information about CD55 on UniProt.org
