Purified anti-mouse CD301 (MGL1/MGL2) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3096	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Purified and recombinant mouse MGL1 and MGL2

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IHC-F, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

LOM-14 recognizes mouse CD301a and CD301b. Additional reported applications (for relevant formats) include: immunohistochemical staining of frozen tissue sections^1-3 and immunoprecipitation⁴.

Application References (PubMed link indicates BioLegend citation)

Denda-Nagai K, et al. 2010. J. Biol. Chem. 285:19193. (IHC)
Sato K, et al. 2005. Blood 106:207. (IHC)
Tsuiji M, et al. 2002. J. Biol. Chem. 277:28892. (IHC)
Kimura T, et al. 1995. J. Biol. Chem. 270:16056. (IP)

Product Citations

Giannoudaki E, et al. 2019. Nat Commun. 3.196527778. PubMed

RRID

AB_2561959 (BioLegend Cat. No. 145702)

Antigen Details

Structure: 42 kD type II transmembrane glycoprotein, contain a cytoplasmic domain, a transmembrane domain, a neck domain, and a carbohydrate recognition domain (CRD)
Distribution: Immature dendritic cells, a subset of macrophages
Function: Cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, tissue remodeling
Interaction: Carbohydrate determinants, GP envelope glycoprotein on Marburg and Ebola viruses
Ligand/Receptor: Glycans containing terminal GalNAc moieties
Cell Type: Dendritic cells, Macrophages
Biology Area: Cell Adhesion, Cell Biology, Immunology, Innate Immunity
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Denda-Nagai K,?et al. 2010. J. Biol. Chem. 285:19193.
2. Westcott D, et al. 2009. J. Exp. Med. 206:3143.
3. Singh SK, et al. 2009. Mol. Immunol. 46:1240.
4. Sakakura M, et al. 2008. J. Biol. Chem. 283:33665.
5. Tsuiji M, et al. 2002. J. Biol. Chem. 277:28892.
Gene ID: 17312 View all products for this Gene ID 216864 View all products for this Gene ID
UniProt: View information about CD301 on UniProt.org

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