Alexa Fluor® 700 anti-human HLA-DR Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1488	1

Product Details

Verified Reactivity

Human

Reported Reactivity

Rhesus

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

human PBL

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 700 under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is highly recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 700 has a maximum emission of 719 nm when it is excited at 633 nm / 635 nm. Prior to using Alexa Fluor? 700 conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Excitation Laser

Red Laser (633 nm)

Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining¹ of frozen sections and formalin-fixed paraffin-embedded sections¹, and immunoprecipitation¹.

Application References (PubMed link indicates BioLegend citation)

Marder RJ, et al. 1985. Lab. Invest. 52:497.
Norton AJ and Isaacson PG. 1987. Am. J. Pathol. 128:225.
Hua ZX, et al. 1998. Hum. Pathol. 29(12):1441.

Product Citations

Weisberg SP, et al. 2020. Cell Reports. 29(12):3916-3932.e5.. PubMed
Ghirelli C, et al. 2010. Blood. 115:5037. PubMed
Sefik E, et al. 2021. Nat Biotechnol. . PubMed

RRID

AB_893573 (BioLegend Cat. No. 327013) AB_893565 (BioLegend Cat. No. 327014)

Antigen Details

Structure: Ig superfamily, MHC class II, heterodimeric transmembrane protein
Distribution: B cells, activated T cells, monocytes/macrophages, dendritic cells, other APCs
Function: Peptide presentation
Ligand/Receptor: CD3/TCR, CD4
Cell Type: Antigen-presenting cells, B cells, Dendritic cells, Macrophages, Monocytes, T cells, Tregs
Biology Area: Immunology, Innate Immunity
Molecular Family: MHC Antigens
Antigen References: 1. Levacher M, et al. 1990. Clin. Exp. Immunol. 81:177.
2. Terstappen L, et al. 1990. J. Leuk. Biol. 48:138.
3. Edwards J, et al. 1985. J. Immunol. 137:490.
4. van Es A, et al. 1984. Transplantation 37:65.
5. O'Doherty U, et al. 1994. Immunology 82:487.
6. Thomas R, et al. 1994. J. Immunol. 153:4016.
7. Grouard G, et al. 1996. Nature 384:364.
Gene ID: 3122 View all products for this Gene ID 3123 View all products for this Gene ID
UniProt: View information about HLA-DR on UniProt.org

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