Purified anti-human CD11b Antibody
- 产品名称：
- Purified anti-human CD11b Antibody
- 产品类别：
- 抗体
- 产品编号：
- 393102
- 产品应用：
- 393102
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- β2 integrins from granulocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
LM2 does not block clone ICRF44 indicating a unique epitope.
- Product Citations
-
- Halder LD, et al. 2020. Nat Commun. 2.077083333. PubMed
- RRID
- AB_2728424 (BioLegend Cat. No. 393102)
- Structure
- Integrin, type I transmembrane glycoprotein, associates with integrin β2 (CD18), 165-170 kD
- Distribution
-
Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subset of T cells, subset of B cells
- Function
- Adhesion, phagocytosis, chemotaxis, neutrophil activation
- Ligand/Receptor
- ICAM-1(CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, factor X
- Cell Type
- Granulocytes, Monocytes, Macrophages, Dendritic cells, NK cells, T cells, B cells, Neutrophils
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Costimulatory Molecules
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Stewart M, et al. 1995. Curr Opin Cell Biol. 7:690.
- Miller LJ, et al. 1986. J Immunol. 137(9):2891.
- Gene ID
- 3684 View all products for this Gene ID
- UniProt
- View information about CD11b on UniProt.org
