Purified anti-SynDIG1 Antibody
- 产品名称：
- Purified anti-SynDIG1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 851801
- 产品应用：
- 851801
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- GST Fusion protein corresponding to the cytoplasmic N-terminus (a.a. 1-183) of mouse SynDIG1.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is more reactive with mouse and rat lysates than human.
Additional reported applications (for the relevant formats) include:?immunocytochemistry (ICC)
- Application References
(PubMed link indicates BioLegend citation) -
- Kalashnikova E, et al. 2010. Neuron. 65(1):80-93.
- RRID
- AB_2728581 (BioLegend Cat. No. 851801) AB_2728582 (BioLegend Cat. No. 851802)
- Structure
- SynDIG1 (Tmem90b) is a 258 amino acid protein with an apparent molecular mass of ~ 29 kD.
- Distribution
-
Tissue distribution: Mainly in the Central Nervous System. Also expressed in muscle and reproductive organs.
Cellular distribution: Plasma Membrane and endosome.
- Function
- SynDIG1 regulates synaptic AMPA receptor content at nascent synapses.
- Interaction
- SynDIG1 forms homodimers in vivo. It also interacts with GRIA1 and GRIA2.
- Biology Area
- Cell Biology, Neuroscience, Synaptic Biology
- Molecular Family
- Adhesion Molecules, Postsynaptic proteins
- Antigen References
-
- Sumioka A. 2013. J. Biochem. 153(4):331.
- Diaz E. 2012. J. Physiol. 590(1):33.
- Gene ID
- 79953 View all products for this Gene ID
- UniProt
- View information about SynDIG1 on UniProt.org
