Purified anti-IP3R1 Antibody (Previously Covance c
- 产品名称：
- Purified anti-IP3R1 Antibody (Previously Covance c
- 产品类别：
- 抗体
- 产品编号：
- 817701
- 产品应用：
- 817701
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a fusion protein corresponding to amino acids 2680-2749 of rat IP3 receptor type 1.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
- Application
-
IHC-P - Quality tested
WB - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10 ?g/mL is suggested.?For Western blotting, the suggested use of this reagent is 1.0 - 10 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is less reactive in human samples than mouse and rat sample in WB.
- Application References
(PubMed link indicates BioLegend citation) -
- Zhao G, et al. 2010. J. Gen. Physiol. 136(3):283-91 (WB)
- Product Citations
-
- Watanabe S, et al. 2016. EMBO Mol Med. 8(12):1421-1437. PubMed
- Howie D, et al. 2019. Front Immunol. 10:1860. PubMed
- RRID
- AB_2564813 (BioLegend Cat. No. 817701)
- Structure
- IP3R1 is a 2758 amino acid protein with an apparent molecular mass of 314 kD.
- Distribution
-
Cellular distribution: Plasma membrane, endoplasmic reticulum, and nucleus.
- Biology Area
- Cell Biology, Neuroscience, Synaptic Biology
- Molecular Family
- Postsynaptic proteins
- Antigen References
-
Tang T-S, et al. 2009. J. Neurosci. 29 (5) 1257-66.
- Gene ID
- 25262 View all products for this Gene ID
- UniProt
- View information about IP3R1 on UniProt.org
