Purified anti-human CD5 Antibody
- 产品名称:
- Purified anti-human CD5 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 364001
- 产品应用:
- 364001
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human T-acute lymphoblastic leukemia (ALL) cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Verified
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. For immunohistochemical staining on frozen tissue sections, the suggested use of this reagent is 5.0 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats): immunoprecipitation1,3,4 and immmunohistochemical staining of frozen and formalin-fixed paraffin-embedded sections2,3,5.
- Application References
(PubMed link indicates BioLegend citation) -
- McAlister MS, et al. 1998. Protein Eng. 11:847. (IP)
- Butmarc JR, et al. 1998. Am. J. Clin. Pathol. 109:682. (IHC)
- Engleman EG, et al. 1981. Proc. Natl. Acad. Sci. USA 78:1791. (IHC, IP)
- Ledbetter JA, et al. 1981. J. Exp. Med. 153:310. (FC, IP)
- Warnke R and Levy R. 1980. J. Histochem. Cytochem. 28:771. (IHC)
- Product Citations
-
- Baran N, et al. 2022. Nat Commun. 13:2801. PubMed
- Cytlak U, et al. 2020. Immunity. 53(2):353-370. PubMed
- RRID
- AB_2564476 (BioLegend Cat. No. 364001) AB_2564477 (BioLegend Cat. No. 364002)
- Structure
- Scavenger receptor superfamily, 67 kD
- Distribution
-
Thymocytes, T cells, and subsets of B and dendritic cells.
- Function
- Modulates TCR and BCR signaling, involved in thymocyte maturation and T-B cell interaction
- Ligand/Receptor
- CD72
- Cell Type
- B cells, Dendritic cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Kipps T. 1989. Adv. Immunol. 47:117.
2. Resnick D, et al. 1994. Trends Biochem. Sci. 1:5.
3. Wood GS and Freudenthal PS. 1992. Am. J. Pathol. 141:789.
- Gene ID
- 921 View all products for this Gene ID
- UniProt
- View information about CD5 on UniProt.org