Biotin anti-human CD1c Antibody
- 产品名称：
- Biotin anti-human CD1c Antibody
- 产品类别：
- 抗体
- 产品编号：
- 331504
- 产品应用：
- 331504
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining on frozen tissue4, 5,?formalin-fixed paraffin-embedded immunohistochemical staining6, and spatial biology (IBEX)7,8.
- Application References
(PubMed link indicates BioLegend citation) -
- del C Salamone M, et al. 2001. J Leukoc Biol. 70:567.
- de Fraissinette A, et al. 1988. Exp Hematol. 16:764.
- Li D, et al. 2012. J Exp Med. 209:109. PubMed
- Xu C, et al. 2010. Am J Hematol. 85:539 (IHC-F)
- Gerlini G, et al. 2001. J Invest Dermatol. 117:576 (IHC-F)
- Poposki J, et al. 2016. Clin Exp Allergy 45:384 (IHC-P) PubMed
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- RRID
- AB_1088997 (BioLegend Cat. No. 331504)
- Structure
- 43 kD, Ig superfamily, MHC I-like molecule, associates with β2-microglobulin
- Distribution
-
B cell subset, cortical thymocytes, dendritic cells, and Langerhans cells
- Function
- Presents lipid antigen to CD1c-restricted T cells
- Ligand/Receptor
- CD1c-restricted TCR
- Cell Type
- B cells, Dendritic cells, Langerhans cells, Thymocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Fainboim LM and del C. Salamone. 2002. J. Biol. Reg. Homeos. Ag. 16:125.
2. M. del Salamone C, et al. 2001. J. Leukocyte Biol. 70:567.
3. Zola H, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. P42.
- Gene ID
- 911 View all products for this Gene ID
- UniProt
- View information about CD1c on UniProt.org
