APC/Cyanine7 anti-human CD1c Antibody
- 产品名称：
- APC/Cyanine7 anti-human CD1c Antibody
- 产品类别：
- 抗体
- 产品编号：
- 331519
- 产品应用：
- 331519
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2052 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining on frozen tissue4, 5,?formalin-fixed paraffin-embedded immunohistochemical staining6, and spatial biology (IBEX)7,8.
- Additional Product Notes
- BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- del C Salamone M, et al. 2001. J Leukoc Biol. 70:567.
- de Fraissinette A, et al. 1988. Exp Hematol. 16:764.
- Li D, et al. 2012. J Exp Med. 209:109. PubMed
- Xu C, et al. 2010. Am J Hematol. 85:539 (IHC-F)
- Gerlini G, et al. 2001. J Invest Dermatol. 117:576 (IHC-F)
- Poposki J, et al. 2016. Clin Exp Allergy 45:384 (IHC-P) PubMed
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Zhou R, et al. 2020. Immunity. S1074-7613(20)30333-2.. PubMed
- Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
- Deckx N, et al. 2016. Innate Immunity. 22: 266 - 273. PubMed
- Grenga I, et al. 2016. Clin Transl Immunology. 0.265972222. PubMed
- Aliu B, et al. 2020. Journal of Neurochemistry. 154(5):486-501. PubMed
- Izmirly AM, et al. 2022. PLoS Pathog. 18:e1009903. PubMed
- Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed
- Heger L, et al. 2018. Front Immunol. 9:744. PubMed
- Gu C, et al. 2021. Front Immunol. 12:678036. PubMed
- Bziat V, et al. 2021. Cell. . PubMed
- Autenrieth S, et al. 2015. Clin Transl Immunology. 4:50. PubMed
- Mascarell L, et al. 2017. Mucosal Immunol. 0.899305556. PubMed
- Berg L, et al. 2015. J Immunol. 195: 1763-1773. PubMed
- Saraiva DP, et al. 2018. Front Immunol. 2.184027778. PubMed
- Breton G, et al. 2015. J Exp Med. 212:401. PubMed
- Kong XF, et al. 2018. Nat Immunol. 19:973. PubMed
- Connors J, et al. 2022. Geroscience. :. PubMed
- Jin J, et al. 2014. PLoS One. 9:104753. PubMed
- Rusconi M, et al. 2017. Sci Rep. 5.745138889. PubMed
- Leylek R, et al. 2020. Cell Rep. 32:108180. PubMed
- RRID
- AB_10643413 (BioLegend Cat. No. 331519) AB_10644008 (BioLegend Cat. No. 331520)
- Structure
- 43 kD, Ig superfamily, MHC I-like molecule, associates with β2-microglobulin
- Distribution
-
B cell subset, cortical thymocytes, dendritic cells, and Langerhans cells
- Function
- Presents lipid antigen to CD1c-restricted T cells
- Ligand/Receptor
- CD1c-restricted TCR
- Cell Type
- B cells, Dendritic cells, Langerhans cells, Thymocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Fainboim LM and del C. Salamone. 2002. J. Biol. Reg. Homeos. Ag. 16:125.
2. M. del Salamone C, et al. 2001. J. Leukocyte Biol. 70:567.
3. Zola H, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. P42.
- Gene ID
- 911 View all products for this Gene ID
- UniProt
- View information about CD1c on UniProt.org
