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Alexa Fluor® 594 anti-human CD171 (L1CAM) Anti
产品名称:
Alexa Fluor® 594 anti-human CD171 (L1CAM) Anti
产品类别:
抗体
产品编号:
371606
产品应用:
371606
[价格]
规格 价格 库存
100µg ¥ 4560 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
SKOV-3 ovarian carcinoma cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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RRID
AB_2632717 (BioLegend Cat. No. 371606)

Antigen Details

Structure
200-220 kD. Several immunoglobulin-like domains and fibronectin-like repeats (type III), linked via a single transmembrane sequence to a conserved cytoplasmic domain.
Distribution

Tetanus-toxin positive neurons, endothelial cells, certain epithelial cells, reticular fibroblasts, colon and breast carcinomas, colon melanoma, tumor cells of neuronal and mesothelial origin.

Function
Adhesion molecule. Homotypic and heterotypic cell-cell interaction in neuronal myelination, neurite outgrowth and regeneration. Axonal guidance, neuronal migration.
Ligand/Receptor
Homophilic interaction with itself and heterophilic binding to integrins, other cell adhesion molecules, extracellular matrix molecules.
Cell Type
Endothelial cells, Epithelial cells, Fibroblasts, Neurons
Biology Area
Cancer Biomarkers, Cell Adhesion, Cell Biology, Immunology, Neuroscience, Synaptic Biology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Wolterink S, et al. 2010. Cancer Res. 70(6):2504.
2. Huszar M, et al. 2006. Human Pathology 37(8):1000.
3. Kaifi JT, et al. 2006. Anticancer Res. 26(2A):1167.
4. Kaifi JT, et al. 2006. Mod. Pathol. 3:399.
5. Meier F, et al. 2006. Int. J. Cancer 119(3)549.
6. Stoeck A, et al. 2006. Biochem. J. 393:609.
7. Gutwein P, et al. 2005. Clin. Cancer Res. 11(7)2492.

Gene ID
3897 View all products for this Gene ID
UniProt
View information about CD171 on UniProt.org

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