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PE anti-human CD108 Antibody
产品名称:
PE anti-human CD108 Antibody
产品类别:
抗体
产品编号:
376603
产品应用:
376603
[价格]
规格 价格 库存
25tests ¥ 2052 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
PHA-activated PBMC
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total ?g amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. New York.
  2. Angelisova P, et al. 1999. Immunobiology 200:234-45.
RRID
AB_2927888 (BioLegend Cat. No. 376603) AB_2927888 (BioLegend Cat. No. 376604)

Antigen Details

Structure
Membrane-bound semaphorin with GPI linkage and contains and IgG like domain, approximately 80kD
Distribution

Widely expressed in spleen, thymus, testis, ovary, heart, lung, kidney, brain, small intestine, red cells, monocytes, and T cells

Function
Modulates inflammation and T-cell-mediated immune responses. Guidance protein involved in central and peripheral axon growth. Interaction with PlexinC1 induces activation of monocytes.
Ligand/Receptor
PlexinC1
Cell Type
Erythrocytes, Monocytes, T cells
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References
  1. Mine, T, et al. 2000. Tissue Antigens. 55: 429–36.
  2. Jeroen Pasterkamp, et al. 2003. Nature. 424:398-405.
  3. Seltsam A, et al. 2007. Transfusion. 47:133-46.
  4. Suzuki K,?et al. 2007. Nature. 446:680-4.
Gene ID
8482 View all products for this Gene ID
UniProt
View information about CD108 on UniProt.org

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