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Purified anti-CD68 Antibody
产品名称:
Purified anti-CD68 Antibody
产品类别:
抗体
产品编号:
916104
产品应用:
916104
[价格]
规格 价格 库存
100µg ¥ 1488 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was generated using a Lysosomal fraction of human alveolar macrophages.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested
IP, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.2 - 5.0 μg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation and western blotting.

The CD68 (clone KP1) monoclonal antibody reacts with a monocyte/macrophage/microglia associated antigen (110 kD) identified as CD68.

Application References

(PubMed link indicates BioLegend citation)
  1. Holness CL, et al. 1993. Blood 81(6):1607.
  2. Horny HP, et al. 1990. J. Clin. Path. 43:719.
  3. Pulford KAF, et al. 1989. J. Clin. Path. 42:414.
Product Citations
  1. Wagner J et al. 2019. Cell. 177(5):1330-1345 . PubMed
  2. Kiniwa T, et al. 2016. Proc Natl Acad Sci U S A. 113: 10139 - 10144. PubMed
  3. Gide TN, et al. 2019. Cancer Cell. 35:238. PubMed
  4. Burlingame EA, et al. 2021. Cell Rep Methods. 1:. PubMed
  5. Gudjonsson JE, et al. 2020. JCI Insight. 5:. PubMed
  6. Xie S, et al. 2020. Ann Transl Med. 1.384027778. PubMed
  7. Wang C, et al. 2022. Signal Transduct Target Ther. 7:289. PubMed
  8. Chevrier S, et al. 2018. Cell Syst. 0.675. PubMed
  9. Johnson BE, et al. 2022. Cell Rep Med. 3:100525. PubMed
RRID
AB_2616797 (BioLegend Cat. No. 916104)

Antigen Details

Structure
Sialomucin family, 110 kD.
Distribution

Microglia, monocytes, macrophages, dendritic cells, granulocytes, subset of hematopoietic progenitors, γ/δ T cells, NK cells, LAK cells, subset of B cells, fibroblasts, and endothelial cells.

Cell Type
B cells, Dendritic cells, Endothelial cells, Fibroblasts, Granulocytes, Hematopoietic stem and progenitors, Macrophages, Microglia, Monocytes
Biology Area
Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Signal Transduction
Molecular Family
CD Molecules
Gene ID
968 View all products for this Gene ID
UniProt
View information about CD68 on UniProt.org

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