Purified anti-human CCRL2 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 2328	1

规格

价格

库存

100µg

￥ 2328

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Expression vector containing the full sequence of CCRL2

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References (PubMed link indicates BioLegend citation)

Migeotte I, et al. 2002. Eur. J. Immunol. 32:494. (FC)

RRID

AB_2562116 (BioLegend Cat. No. 358302)

Antigen Details

Structure: Seven transmembrane, G-protein coupled receptor, 2 isoforms
Distribution: Majority of cell types of hematopoietic origin, including monocytes, macrophages, neutrophils, lymphocytes, and NK cells; upregulated after inflammatory stimuli
Function: May act as a decoy receptor capturing and endocyting its ligands; captures chemerin/RARRES2 on the cell surface to present it to neighboring cells
Ligand/Receptor: CCL5, CCL19, chemerin/RARRES2
Cell Type: B cells, Dendritic cells, Neutrophils
Biology Area: Cell Biology, Immunology
Molecular Family: Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Yin F, et al. 2012. Biochem. Biophys. Res. Commun. 429:168.
2. An P, et al. 2011. PLoS Genet. 10:e1002328.
3. Yoshimura T and Oppenheim JJ. 2011. Exp. Cell. Res. 317:674.
Gene ID: 9034 View all products for this Gene ID
UniProt: View information about CCRL2 on UniProt.org

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