PE anti-human CCRL2 Antibody
- 产品名称：
- PE anti-human CCRL2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 358303
- 产品应用：
- 358303
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1836 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Expression vector containing the full sequence of CCRL2
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Migeotte I, et al. 2002. Eur. J. Immunol. 32:494. (FC)
- Product Citations
-
- Karantanos T, et al. 2022. Sci Adv. 8:eabl8952. PubMed
- RRID
- AB_2562117 (BioLegend Cat. No. 358303) AB_2562118 (BioLegend Cat. No. 358304)
- Structure
- Seven transmembrane, G-protein coupled receptor, 2 isoforms
- Distribution
- Majority of cell types of hematopoietic origin, including monocytes, macrophages, neutrophils, lymphocytes, and NK cells; upregulated after inflammatory stimuli
- Function
- May act as a decoy receptor capturing and endocyting its ligands; captures chemerin/RARRES2 on the cell surface to present it to neighboring cells
- Ligand/Receptor
- CCL5, CCL19, chemerin/RARRES2
- Cell Type
- B cells, Dendritic cells, Neutrophils
- Biology Area
- Cell Biology, Immunology
- Molecular Family
- Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Yin F, et al. 2012. Biochem. Biophys. Res. Commun. 429:168.
2. An P, et al. 2011. PLoS Genet. 10:e1002328.
3. Yoshimura T and Oppenheim JJ. 2011. Exp. Cell. Res. 317:674.
- Gene ID
- 9034 View all products for this Gene ID
- UniProt
- View information about CCRL2 on UniProt.org
