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PE anti-human GPR83 Antibody
产品名称:
PE anti-human GPR83 Antibody
产品类别:
抗体
产品编号:
363305
产品应用:
363305
[价格]
规格 价格 库存
25tests ¥ 1836 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
DNA vaccine with full coding sequence of human GPCR cloned in expression vector.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2564580 (BioLegend Cat. No. 363305) AB_2564581 (BioLegend Cat. No. 363306)

Antigen Details

Structure
Orphan GPR, homologous to tachykinin and neuropeptide Y (NPY) receptors. Belongs to the G-protein coupled receptor 1 family and is approximately 48 kD.
Distribution
Found on neurons in the brain and Tregs.
Function
Induces Foxp3 expression in CD4+ T cells, and may be involved in thermoregulation.
Interaction
Forms a heterodimer with Ghsr1a or homodimerizes.
Cell Type
Neurons, Tregs
Biology Area
Immunology
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References

1. De Moerlooze L, et al. 2000. Cytogenet. Cell Genet. 90:146.
2. Hansen W, et al. 2006. J. Immunol. 177:209.
3. Sugimoto N et al. 2006. Int. Immunol. 18:1197.
4. Lu LF, et al. 2007. Mol. Cell Biol. 27: 8065.
5.?Müller TD, et al. 2013. Nat. Commun. 4:1968.?

Gene ID
10888 View all products for this Gene ID
UniProt
View information about GPR83 on UniProt.org

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