PE anti-human CD192 (CCR2) Antibody
- 产品名称：
- PE anti-human CD192 (CCR2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 357205
- 产品应用：
- 357205
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1836 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR2 DNA immunogen
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Epitope of clone K036C2 has been mapped to amino acids 11-29 and 21-39 of human CCR2.
- Application References
(PubMed link indicates BioLegend citation) -
- Tanaka T,?et al. 2022. Monoclon Antib Immunodiagn Immunother. 41(5):285-289 (Epitope)
- Product Citations
-
- Arlehamn C, et al. 2014. J Immunol. 193:2931. PubMed
- Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
- Wu Y, et al. 2022. J Cancer Res Clin Oncol. . PubMed
- Day P et al. 2019. Br J Pharmacol. 176(15):2736-2749 . PubMed
- Fang WB, et al. 2021. Sci Rep. 11:8708. PubMed
- Seo IH, et al. 2021. Cell Reports. 36(4):109438. PubMed
- Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
- Lavin Y et al. 2017. Cell. 169(4):750-765 . PubMed
- RRID
- AB_2562058 (BioLegend Cat. No. 357205) AB_2562059 (BioLegend Cat. No. 357206)
- Structure
- Chemokine receptor, GPCR, seven transmembrane receptor
- Distribution
-
Monocytes, macrophages, immature dendritic cells, memory T cells
- Function
- Induces monocyte adhesion to endothelial cells and chemotaxis
- Ligand/Receptor
- CCL2 (MCP-1), CCL7 (MCP-3), CCL8 (MCP-2), CCL13 (MCP-4), CCL16 (HCC4)
- Cell Type
- Dendritic cells, Macrophages, Monocytes, T cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Wong LM, et al. 1997. J. Biol. Chem. 272:1038.
2. Papadopoulou C, et al. 2008. Cytokine 43:181.
3. Barlic J, et al. 2007. J. Leukoc. Biol. 82:226.
4. Gu L, et al. 1998. Mol. Cell 2:275.
5. Volpe S, et al. 2012. PLoS One. 7:e37208.
- Gene ID
- 729230 View all products for this Gene ID
- UniProt
- View information about CD192 on UniProt.org
