Biotin anti-human CD192 (CCR2) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 3180	1

规格

价格

库存

100µg

￥ 3180

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

CCR2 DNA immunogen

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Epitope of clone K036C2 has been mapped to amino acids 11-29 and 21-39 of human CCR2.

Application References (PubMed link indicates BioLegend citation)

Tanaka T,?et al. 2022. Monoclon Antib Immunodiagn Immunother. 41(5):285-289 (Epitope)

RRID

AB_2566753 (BioLegend Cat. No. 357224)

Antigen Details

Structure: Chemokine receptor, GPCR, seven transmembrane receptor
Distribution: Monocytes, macrophages, immature dendritic cells, memory T cells
Function: Induces monocyte adhesion to endothelial cells and chemotaxis
Ligand/Receptor: CCL2 (MCP-1), CCL7 (MCP-3), CCL8 (MCP-2), CCL13 (MCP-4), CCL16 (HCC4)
Cell Type: Dendritic cells, Macrophages, Monocytes, T cells
Biology Area: Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Wong LM, et al. 1997. J. Biol. Chem. 272:1038.
2. Papadopoulou C, et al. 2008. Cytokine 43:181.
3. Barlic J, et al. 2007. J. Leukoc. Biol. 82:226.
4. Gu L, et al. 1998. Mol. Cell 2:275.
5. Volpe S, et al. 2012. PLoS One. 7:e37208.
Gene ID: 729230 View all products for this Gene ID
UniProt: View information about CD192 on UniProt.org

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