APC anti-human CD192 (CCR2) Antibody
- 产品名称：
- APC anti-human CD192 (CCR2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 357207
- 产品应用：
- 357207
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1788 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- CCR2 DNA immunogen
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Epitope of clone K036C2 has been mapped to amino acids 11-29 and 21-39 of human CCR2.
- Application References
(PubMed link indicates BioLegend citation) -
- Tanaka T,?et al. 2022. Monoclon Antib Immunodiagn Immunother. 41(5):285-289 (Epitope)
- Product Citations
-
- Gabriely G, et al. 2021. iScience. 24:103347. PubMed
- Hoang A, et al. 2014. J Leukoc Biol. 96:481. PubMed
- Mandl M, et al. 2014. PLoS One. 9:112140. PubMed
- Idorn M, et al. 2018. Oncoimmunology. 7:e1412029. PubMed
- Cohen CA, et al. 2021. Nat Commun. 12:4678. PubMed
- Gonzalo–Gil E, et al. 2019. Elife. 8:e44360. PubMed
- Yin S, et al. 2015. Sci Rep. 5: 14432. PubMed
- Berry MR et al. 2017. Cell. 170(5):860-874 . PubMed
- Tian Z, et al. 2022. Cancer Cell Int. 22:362. PubMed
- Huang T, et al. 2020. Front Oncol. 10:19. PubMed
- Yang J, et al. 2018. Mediators Inflamm. 2018:9031452. PubMed
- Yao W, et al. 2017. EBioMedicine. 10.1016/j.ebiom.2017.07.014. PubMed
- RRID
- AB_2562238 (BioLegend Cat. No. 357207) AB_2562239 (BioLegend Cat. No. 357208)
- Structure
- Chemokine receptor, GPCR, seven transmembrane receptor
- Distribution
-
Monocytes, macrophages, immature dendritic cells, memory T cells
- Function
- Induces monocyte adhesion to endothelial cells and chemotaxis
- Ligand/Receptor
- CCL2 (MCP-1), CCL7 (MCP-3), CCL8 (MCP-2), CCL13 (MCP-4), CCL16 (HCC4)
- Cell Type
- Dendritic cells, Macrophages, Monocytes, T cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Wong LM, et al. 1997. J. Biol. Chem. 272:1038.
2. Papadopoulou C, et al. 2008. Cytokine 43:181.
3. Barlic J, et al. 2007. J. Leukoc. Biol. 82:226.
4. Gu L, et al. 1998. Mol. Cell 2:275.
5. Volpe S, et al. 2012. PLoS One. 7:e37208.
- Gene ID
- 729230 View all products for this Gene ID
- UniProt
- View information about CD192 on UniProt.org
