首页 > 抗体蛋白 > 抗体
Purified anti-rat CD28 Antibody
产品名称:
Purified anti-rat CD28 Antibody
产品类别:
抗体
产品编号:
200902
产品应用:
200902
[价格]
规格 价格 库存
500µg ¥ 3036 1

产品详情

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Rat CD28-transfected BALB/c mouse A2OJ cell line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The JJ319 antibody has been reported to augment in vitro T cell proliferation and enhance IL-2 production. Additional reported applications (for the relevant formats) include: immunoprecipitation, in vitro costimulation of proliferation responses1, and in vitro costimulation of IL-2 production in the presence of R73 antibody (anti-rat a/? TCR, Cat. No. 201112)2.

Application References

(PubMed link indicates BioLegend citation)
  1. Tacke M, et al. 1995. J. Immunol. 154:5121. (Costim)
  2. Tacke M, et al. 1997. Eur. J. Immunol. 27:239. (Costim)
  3. Du Y, et al. 2012. PLoS One. 7:e52911. PubMed.
Product Citations
  1. Kumar RK, et al. 2021. Vascul Pharmacol. 138:106838. PubMed
  2. Du Y, et al. 2012. PLoS One. 7:e52911. PubMed
  3. Reese SR, et al. 2021. Transplantation. 105:1516. PubMed
RRID
AB_313891 (BioLegend Cat. No. 200902)

Antigen Details

Structure
Ig superfamily, 44 kD
Distribution

All α/βTCR+ T cells, most γ/δTCR+ T cells, NK cell subset

Function
T cell costimulation
Ligand/Receptor
CD80 (B7-1) and CD86 (B7-2)
Cell Type
T cells, NK cells
Biology Area
Immunology, Costimulatory Molecules
Molecular Family
CD Molecules
Antigen References

1. Tacke M, et al. 1995. J. Immunol. 154:5121.
2. Mitnancht R, et al. 1995. Eur. J. Immunol. 25:328.
3. Tacke M, et al. 1997. Eur. J. Immunol. 27:239.

Gene ID
25660 View all products for this Gene ID
UniProt
View information about CD28 on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线