Purified anti-mouse CD74 (CLIP) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
500µg	￥ 3876	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IHC-F, IP, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This clone is also known as In1 and In-1. Additional reported applications (for the relevant formats) include: immunohistochemistry¹, immunoprecipitation³, and western blotting⁴.

Application References (PubMed link indicates BioLegend citation)

Momburg F, et al. 1986. J. Immunol. 136:940. (IHC)
Takahashi K, et al. 2009. Respir. Res. 10:33. (FC)
Meza-Romero R, et al. 2014. J. Immunol. 192:4164. (IP)
Heinrichs D, et al. 2011. Proc. Natl. Acad. Sci. USA 108:17444. (WB)

Product Citations

Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
Baranov MV, et al. 2018. iScience. 11:160. PubMed
Cho CS, et al. 2021. Cell. 184(13):3559-3572.e22. PubMed

RRID

AB_2566502 (BioLegend Cat. No. 151002)

Antigen Details

Structure: 33.5 kD and homotrimer.
Distribution: B-cells, monocytes/macrophages, dendritic cells, activated T-cells, and activated endothelial/epithelial cells.
Function: MHC class II chaperone, MHC class II molecule sorting, and peptide loading.
Interaction: MHC class II molecules and peptides.
Ligand/Receptor: Macrophage migration inhibitory factor (MIF).
Cell Type: B cells, Dendritic cells, Endothelial cells, Epithelial cells, Macrophages, Monocytes, T cells
Biology Area: Immunology
Molecular Family: CD Molecules, MHC Antigens
Antigen References: 1. Herrero L, et al. 2013. Arthritis Rheum. 65:2724.
2. Geneve L, et al. 2012. Int. Immunol. 24:645.
3. Sille FC, et al. 2011. Immunol Lett. 139:33.
4. Shih NY, et al. 1995. Mol. Immunol. 32:643.
5. Shi X, et al. 2006. Immunity 25:595.
6. Starlets D, et al. 2006. Blood 107:4807.
Gene ID: 16149 View all products for this Gene ID
UniProt: View information about CD74 on UniProt.org

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