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Purified anti-human IgD Antibody
产品名称:
Purified anti-human IgD Antibody
产品类别:
抗体
产品编号:
348202
产品应用:
348202
[价格]
规格 价格 库存
500µg ¥ 1560 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human IgD
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraformaldehyde fixed frozen sections4?and spatial biology (IBEX)5,6.

Application References

(PubMed link indicates BioLegend citation)
  1. Chen K, et al. 2009. Nat. Immunol. 10:889.
  2. Lee CH, et al. 2005. J. Exp. Med. 203:63.
  3. Sutter JA, et al. 2008. Clin. Immunol. 126:282.
  4. Li H and Pauza CD. 2015. Eur. J. Immunol. 45:298. (IHC)
  5. Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
  6. Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
Product Citations
  1. Taft J, et al. 2021. Cell. 184(17):4447-4463.e20. PubMed
  2. Alroqi F, et al. 2017. J Clin Immunol. . 10.1007/s10875-017-0451-1. PubMed
  3. Chakhtoura M, et al. 2021. PLoS Pathog. 17:e1009732. PubMed
  4. Mann ER, et al. 2020. Sci Immunol. :5. PubMed
  5. Kaufmann M, et al. 2021. Med. 2(3):296-312.e8. PubMed
  6. Gruber CN, et al. 2020. Immunity. 53(3):672-684. PubMed
  7. Jung Y, et al. 2021. Nat Commun. 12:3872. PubMed
  8. Gunawan M, et al. 2017. Sci Rep. . 10.1038/s41598-017-16999-7. PubMed
  9. Eccles JD, et al. 2020. Cell Rep. 30:351. PubMed
  10. Newell KL, et al. 2021. PLoS One. 16:e0244855. PubMed
  11. Henrick BM, et al. 2021. Cell. . PubMed
  12. Martin E, et al. 2020. JCI Insight. :5. PubMed
RRID
AB_10550095 (BioLegend Cat. No. 348202)

Antigen Details

Structure
Exists in a transmembranal and a soluble form
Distribution

Na?ve B cells

Function
Antigen binding, B cell activation
Interaction
The CD79a/CD79b heterodimer
Cell Type
B cells
Biology Area
Immunology
Antigen References

1. Geisberger R, et al. 2006. Immunology 118:429.
2. Weller S, et al. 2005. Eur. J. Immunol. 35:2789.
3. Brandtzaeg P and Johansen FE. 2005. Immunol. Rev. 206:32.

Gene ID
3495 View all products for this Gene ID
UniProt
View information about IgD on UniProt.org

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