Purified anti-human CD161 Antibody
- 产品名称：
- Purified anti-human CD161 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 339902
- 产品应用：
- 339902
- Verified Reactivity
- Human, Cynomolgus, Rhesus
- Reported Reactivity
- African Green, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human NK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
CyTOF? - Verified
WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: inhibition of cytokine production and Western blotting under nonreducing conditions.
- Application References
(PubMed link indicates BioLegend citation) -
- Gum? M, et al. 2004. Blood 104:3664.
- Exley M, et al. 1998. J. Exp. Med. 188:867.
- Marquez C, et al. 1998. Blood 91:2760.
- Product Citations
-
- Rouers A, et al. 2021. Cell Rep Med. 2:100278. PubMed
- Volchenkov R, et al. 2017. Front Immunol. 0.818055556. PubMed
- Martin JC, et al. 2020. Cell. 178(6):1493-1508.e20.. PubMed
- Gruber CN, et al. 2020. Cell. 183:982. PubMed
- Niu C, et al. 2021. Front Immunol. 12:658562. PubMed
- Wastyk HC, et al. 2021. Cell. 184(16):4137-4153.e14. PubMed
- Sattler A, et al. 2021. Am J Transplant. 21:87. PubMed
- Marrero I, et al. 2020. Alcohol Clin Exp Res. 44:1061. PubMed
- Chng MHY, et al. 2020. Immunity. 51(6):1119-1135.e5.. PubMed
- Ardain A, et al. 2019. Nature. 570:528. PubMed
- Cardoso V, et al. 2017. Nature. 549:277. PubMed
- NULL, et al. 2022. Cell. 185:916. PubMed
- Schwabenland M, et al. 2021. Immunity. . PubMed
- Mathewson ND, et al. 2021. Cell. 184(5):1281-1298.e26. PubMed
- Martin E, et al. 2020. JCI Insight. :5. PubMed
- Lavin Y et al. 2017. Cell. 169(4):750-765 . PubMed
- RRID
- AB_1501090 (BioLegend Cat. No. 339902)
- Structure
- Type II glycoprotein, 40-44 kD homodimer, C-type lectin superfamily
- Distribution
-
NK cells, T subset, subset of CD3+ thymocytes
- Ligand/Receptor
- LLT-1 (Lectin-like transcript-1)
- Cell Type
- NK cells, T cells, Thymocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- CD Molecules
- Antigen References
-
1. Takahashi T, et al. 2006. J. Immunol. 176:211.
2. Cosmi L, et al. 2008. J. Exp. Med. 205:1903.
3. Aldemir H, et al. 2005. J. Immunol. 175:7791.
4. Rosen DB, et al. 2008. J. Immunol. 180:6508.
- Gene ID
- 3820 View all products for this Gene ID
- UniProt
- View information about CD161 on UniProt.org
