PE anti-human CD57 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1548	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Membrane extract of human lymphoblastoid cell line HSB-2.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application Notes

Additional reported applications for the relevant formats include: Western blotting¹.

Application References (PubMed link indicates BioLegend citation)

Yoshihara Y, et al. 1991. J. Cell Biol. 115:731. (WB)
Abo T, et al. 1981. J. Immunol. 127:1024.
Abo T, et al. 1982. J. Immunol. 129:1752.
Abo T, et al. 1982. J. Immunol. 129:1758.

Product Citations

Jarosch S, et al. 2022. STAR Protoc. 3:101374. PubMed
Scherpenisse M, et al. 2021. MBio. 12:. PubMed
Salumets A, et al. 2022. Aging Cell. 21:e13607. PubMed
Jia L, et al. 2022. Ann Transl Med. 10:482. PubMed

RRID

AB_2562758 (BioLegend Cat. No. 359611) AB_2562759 (BioLegend Cat. No. 359612)

Antigen Details

Structure: Oligosaccharide antigenic determinant present on a variety of proteins, lipids, and chrondroitin sulfate proteoglycans, 100-115 kD. The antigen is conserved across species.
Distribution: CD57 antigen is expressed on a subset of peripheral blood lymphocytes including a subset of NK cells and a subset of CD8⁺ T cells. Also expressed on neural cells and striated muscle.
Function: Unknown function, may be involved in cell-matrix interactions.
Ligand/Receptor: Binds to L-selectin and P-selectin in a calcium-dependent manner, also binds to second globular domain of E8 laminin fragment.
Cell Type: Lymphocytes, NK cells, T cells
Biology Area: Immunology, Costimulatory Molecules
Molecular Family: CD Molecules
Antigen References: 1. Schubert J, et al. 1989. In Leucocyte Typing IV (Knapp W, ed) Oxford University Press Oxford pp 711-714.
2. Palmer BE, et al. 2005. J. Immunol. 175:8415.
3. Schachner M, et al. 1995. Trends Neurosci. 18:183.
4. Wood KL, et al. 2005. Clin. Immunol. 117:294.
Gene ID: 27087 View all products for this Gene ID
UniProt: View information about CD57 on UniProt.org

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