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Purified anti-mouse CD49b (Maxpar® Ready) Anti
产品名称:
Purified anti-mouse CD49b (Maxpar® Ready) Anti
产品类别:
抗体
产品编号:
103513
产品应用:
103513
[价格]
规格 价格 库存
100µg ¥ 1272 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse colon carcinoma cell line Colon26
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1.0 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
CyTOF? - Verified

Recommended Usage

This product is suitable for use with the?Maxpar? Metal Labeling Kits.?For metal labeling using Maxpar? Ready antibodies,?proceed directly to the step to Partially Reduce the Antibody by adding 100 ?l of Maxpar? Ready antibody to 100 ?l of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar? User Guide when conjugating Maxpar? Ready antibodies.

Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunofluorescence on frozen sections4, and blocking of cell adhesion1-3. The Ultra-LEAF? purified antibody (Endotoxin < 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 103525 & 103526).

Additional Product Notes

Maxpar? is a registered trademark of Standard BioTools Inc.

Application References

(PubMed link indicates BioLegend citation)
  1. Miyake S, et al. 1994. Eur. J. Immunol. 24:2000. (Block, IP)
  2. Noto K, et al. 1995. Int. Immunol. 7:835. (Block)
  3. Arase H, et al. 2001. J. Immunol. 167:1141. (Block)
  4. Zhang Z, et al. 2008. Blood 111:1980. (IF)
Product Citations
  1. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  2. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  3. Janela B, et al. 2019. Immunity. 50:1069. PubMed
RRID
AB_2563754 (BioLegend Cat. No. 103513)

Antigen Details

Structure
Integrin family, associates with CD29 (β1 integrin), 150 kD
Distribution

NK cells, subset splenic CD4+ T cells, NK-T cells, intestinal intraepithelial and lamina propria lymphocytes, epithelial cells, platelets

Function
Adhesion, lymphocyte activation
Ligand/Receptor
Collagen, laminin, fibronectin
Cell Type
Epithelial cells, Lymphocytes, NK cells, NKT cells, Platelets, T cells
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Sasaki K, et al. 2003. Int. Immunol. 15:701.
3. Inoue O, et al. 2003. J. Cell Biol. 160:769.

Gene ID
16398 View all products for this Gene ID
UniProt
View information about CD49b on UniProt.org

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