APC anti-mouse CD49a Antibody
- 产品名称：
- APC anti-mouse CD49a Antibody
- 产品类别：
- 抗体
- 产品编号：
- 142605
- 产品应用：
- 142605
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- Mouse Neuroblastoma Cell Line C1300
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant format) include: inhibition of cell adhesion and cytokine production1,2.
- Application References
(PubMed link indicates BioLegend citation) -
- Miyake S, et al. 1994. Eur. J. Immunol. 24:2000. (FC, Block)
- Tanaka T, et al. 1995. Int. Immunol. 7:1183. (Block)
- Product Citations
-
- B?ttcher JP, et al. 2018. Cell. 172:1022. PubMed
- Cassidy BR, et al. 2020. J Neuroinflammation. 17:259. PubMed
- McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
- Nabekura T, et al. 2020. Immunity. 96:52. PubMed
- Tripathi D, et al. 2016. Nat Commun. 7:13896. PubMed
- RRID
- AB_2562252 (BioLegend Cat. No. 142605) AB_2562253 (BioLegend Cat. No. 142606)
- Structure
- 1179 aa, type I transmembrane glycoprotein
- Distribution
-
Endothelial cells, fibroblasts, activated T cells
- Function
- Leukocyte adhesion and homing; costimulation
- Ligand/Receptor
- Collagens, laminin
- Cell Type
- Endothelial cells, Fibroblasts, Mesenchymal Stem Cells, T cells
- Biology Area
- Angiogenesis, Cell Adhesion, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity, Signal Transduction, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Barczyk M, et al. 2010. Cell Tissue Res. 339:269.
- Gene ID
- 109700 View all products for this Gene ID
- UniProt
- View information about CD49a on UniProt.org
