APC anti-mouse Notch 4 Antibody
- 产品名称：
- APC anti-mouse Notch 4 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 128413
- 产品应用：
- 128413
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- Notch4-Fc recombinant protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g/test. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Moriyama Y, et al.2008. Intl J. Immunol. 20:763.
- Reilla LV, et al. 2011. J. Immunol. 187:4629. PubMed.
- Product Citations
-
- Riella L, et al. 2011. J Immunol. 187:4629. PubMed
- RRID
- AB_2151253 (BioLegend Cat. No. 128413)
- Structure
- Type 1 transmembrane receptor with a large extracellular domain consisting of 29 -36 EGF( epidermal growth factor) and three LNR (Lin12-Notch) repeats.
- Distribution
-
Notch 4 is preferentially expressed in endothelial cells.
- Function
- Regulation of cell development, including myogenesis, neurogenesis, and lymphocyte development. Notch 4 seems to play a crucial role in vasculogenesis and angiogenesis.
- Ligand/Receptor
- Jagged 1, Jagged2, Delta-like 1, Delta-like3 and Delta-like 4
- Cell Type
- Endothelial cells
- Biology Area
- Immunology
- Antigen References
-
1.Ehebauer MT,et al. 2006. Biochem J.392:13.
2.Shimizu K,et al. 2000.Mol Cell Biology. 20:18
3. Tanigaki K,et al.2007. Nature immunol. 8:451.
- Gene ID
- 18132 View all products for this Gene ID
- UniProt
- View information about Notch 4 on UniProt.org
