Ultra-LEAF™ Purified anti-mouse B7-H4 (B7S1,
- 产品名称：
- Ultra-LEAF™ Purified anti-mouse B7-H4 (B7S1,
- 产品类别：
- 抗体
- 产品编号：
- 139409
- 产品应用：
- 139409
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- Mouse B7-H4 human IgG1 Fc fusion protein
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.06 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2832506 (BioLegend Cat. No. 139409) AB_2832507 (BioLegend Cat. No. 139410)
- Structure
- Belongs to the B7 family, contains two extracellular Ig-like domains.
- Distribution
-
Induced to express on T cells, B cells, macrophages, and dendritic cells. It is also expressed on some tumor cancer cells.
- Function
- Inhibit T cell activation, cell cycle progression, and cytokine production.
- Cell Type
- B cells, Dendritic cells, Macrophages, T cells
- Biology Area
- Costimulatory Molecules, Immunology, Innate Immunity
- Antigen References
-
1. Choi IH, et al. 2003. J. Immunol. 171:4650.
2. Prasad DV, et al. 2003. Immunity 18:863.
3. Kryczek I, et al. 2006. J. Exp. Med. 203:871.
- Gene ID
- 242122 View all products for this Gene ID
- UniProt
- View information about B7-H4 on UniProt.org
