APC anti-mouse B7-H4 (B7S1, B7X) Antibody
- 产品名称：
- APC anti-mouse B7-H4 (B7S1, B7X) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 139407
- 产品应用：
- 139407
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- Mouse B7-H4 human IgG1 Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Chen L, et al. 2020. Cancer Immunol Res. 0.457638889. PubMed
- RRID
- AB_2565217 (BioLegend Cat. No. 139407) AB_2565218 (BioLegend Cat. No. 139408)
- Structure
- Belongs to the B7 family, contains two extracellular Ig-like domains.
- Distribution
-
Induced to express on T cells, B cells, macrophages, and dendritic cells. It is also expressed on some tumor cancer cells.
- Function
- Inhibit T cell activation, cell cycle progression, and cytokine production.
- Cell Type
- B cells, Dendritic cells, Macrophages, T cells
- Biology Area
- Costimulatory Molecules, Immunology, Innate Immunity
- Antigen References
-
1. Choi IH, et al. 2003. J. Immunol. 171:4650.
2. Prasad DV, et al. 2003. Immunity 18:863.
3. Kryczek I, et al. 2006. J. Exp. Med. 203:871.
- Gene ID
- 242122 View all products for this Gene ID
- UniProt
- View information about B7-H4 on UniProt.org
